Gene description for THBD |
Gene name |
thrombomodulin |
Gene symbol |
THBD |
Other names/aliases |
AHUS6 BDCA-3 BDCA3 CD141 THPH12 THRM TM |
Species |
Homo sapiens |
Experiment description of studies that identified THBD in Endothelial cells |
1
|
Experiment ID | 223 |
Identified molecule | protein
|
Extracellular vesicle type | Microparticles |
MISEV | EVs |
Identification method | FACS
|
PubMed ID |
10393703
|
Organism | Homo sapiens |
Experiment description | In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant |
Authors | Combes V, Simon AC, Grau GE, Arnoux D, Camoin L, Sabatier F, Mutin M, Sanmarco M, Sampol J, Dignat-George F |
Journal name |
J Clin Invest
|
Publication year | 1999 |
Sample | Endothelial cells |
Sample name | HUVECS |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | FACS Western blotting |
EV-TRACK |
-
|
|
|
2
|
Experiment ID | 551 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes/Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
24009886
|
Organism | Homo sapiens |
Experiment description | Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes. |
Authors | de Jong OG, Verhaar MC, Chen Y, Vader P, Gremmels H, Posthuma G, Schiffelers RM, Gucek M, van Balkom BW. |
Journal name |
J Extracell Vesicles
|
Publication year | 2012 |
Sample | Endothelial cells |
Sample name | Stressed (hypoxia, TNF-alpha-induced activation, high glucose and mannose concentrations)-Endothelial cells (HMEC-1) |
Isolation/purification methods | - |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV120004: EV-METRIC:67%
|
|
|